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How to Clone a Mammoth: The Science of De-Extinction, by Beth Shapiro
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Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?
Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.
Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.
- Sales Rank: #244412 in Books
- Brand: Shapiro Beth
- Published on: 2016-09-20
- Original language: English
- Number of items: 1
- Dimensions: 7.90" h x .80" w x 5.20" l, .0 pounds
- Binding: Paperback
- 240 pages
- How to Clone a Mammoth The Science of de Extinction
From School Library Journal
According to this book, the future of Shapiro's field, "ancient DNA," lies in adapting existing species to survive in threatened environments-think of an elephant refit with the woolly mammoth's coat, relocated in the Arctic tundra. Sounds fantastic, as in unbelievable: although de-extinction was the stuff of science fiction once, advances in genome research have made it more realistic than cloning, the author argues. Many of her colleagues have tried- and failed-to bring back the bucardo, the dodo, the moa, the Lazarus frog, and the carrier pigeon, to name a few whose stories Shapiro honors simply by retelling them. This eye-opening narrative will give teens an inside look at the various facets of scientific research: discipline, ambition, imagination, disappointment, and danger. For example, in 2007 Japan, a 42,000-year-old baby mammoth-so well preserved that "her stomach still contained traces of her mother's milk"-excited researchers, who immediately named her Lyuba. But her DNA was useless, and so their endeavor was short-lived. The future, Shapiro believes, is in de-extinction, which alters existing species in the name of preservation and which, she acknowledges, carries a heavy responsibility in itself. The nonfiction work's 16 color plates and illustrations throughout add to its appeal. VERDICT For students who are interested in environmental issues, who like animals, or who think science is "boring," this book is pretty irresistible.-Georgia Christgau, Middle College High School, Long Island City, NYα(c) Copyright 2011. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.
Review
Winner of the 2016 PROSE Award in Popular Science & Popular Mathematics, Association of American Publishers
2016 Gold Medal Winner in Science, Independent Publisher Book Awards
Winner of the 2016 AAAS/Subaru SB&F Prize for Excellence in Science Books, Young Adult Science Books
One of The Independent’s 6 Best Books in Science 2015
Shortlisted for the 2016 Phi Beta Kappa Award in Science, Phi Beta Kappa Society
Finalist for the 2015 Los Angeles Times Book Prize in Science & Technology
One of Flavorwire’s 10 Must-Read Academic Books for 2015
One of NewScientist.com CultureLab’s Best Reads from 2015
One of Science News’ Favorite Books of 2015
"Beth Shapiro . . . has produced a fascinating book. . . . For anyone who wants a thorough understanding of the technical issues involved in de-extinction, How to Clone a Mammoth should satisfy your curiosity."--Carl Zimmer, Wall Street Journal
"Shapiro . . . Lays out a well-articulated argument for the ‘resurrection of ecological interactions' as the most appropriate goal of de-extinction research. . . . Her professorial voice shines in her thoughtful roadmap for practical decision making in theory-heavy science, as well as in her efforts to 'separate the science of de-extinction from the science fiction of de-extinction.' Readers will emerge with the ability to think more deeply about the facts of de-extinction and cloning at a time when hyperbolic and emotionally manipulative claims about such scientific breakthroughs are all too common."--Publishers Weekly
"[A] disturbing and thoughtful new book. . . . Shapiro makes a good, sensible, balanced case."--Cathy Gere, The Nation
"[A] clear appraisal of what it would really take to resurrect extinct species. . . . Several hurdles remain, and Shapiro presents these clearly and entertainingly as a brilliant thought experiment at the boundaries of biological plausibility."--Henry Nicholls, Nature
"As Shapiro sees it, de-extinction isn't about geeky genetic sleight of hand or about the resurrection of legendary beasts; it's a valuable new tool for conserving and enriching the global ecosystem."--Natural History
"In this lucid road map for the nascent discipline of ‘de-extinction,' Shapiro, an evolutionary biologist, examines not only how we can resurrect long-vanished species but also when we cannot or should not."--Scientific American
"As a researcher who is shaping this field, Shapiro is the perfect guide to the ongoing discussion about de-extinction. While many news items and conference presentations have focused on the technology required to create extinct life, Shapiro carefully considers every step along the journey to de-extinction, from choosing a species to revive to making sure they don't become extinct all over again….Whether you're all for de-extinction or against it, Shapiro's sharp, witty, and impeccably-argued book is essential for informing those who will decide what life will become."--Briant Switek, National Geographic.com's Laelaps blog
"[Shapiro] goes to great lengths to demystify the art and science of cloning."--Kirkus Reviews
"Some of the best conversations I've had in recent months have come about while discussing de-extinction. The concept is simple: should we clone extinct animals, Jurassic Park-style, from found genetic material? How do we do it? What would the impact be on the environment? Shapiro makes it clear that we should have this discussion now because the future of de-extinction is real and coming fast."--Andrew Sturgeon, Flavorwire, from "10 Must-Read Academic Books of 2015"
"[A] fascinating book. . . . A great popular science title, and one that makes it clear that a future you may have imagined is already underway."--Library Journal, starred review
"In How to Clone a Mammoth, Shapiro provides detailed descriptions of current state-of-the-art bioengineering technologies, explaining just what can and cannot be done. She also provides a thorough discussion of the ethical and environmental issues raised by de-extinction proposals. Readers of the book will be well equipped to develop their own informed opinions on this controversial topic."--Ravi Mandalia, Techie News
"In How to Clone a Mammoth, molecular paleontologist Beth Shapiro spells out, step by step, how and how soon real scientists might be able to bring an extinct species back to life."--Nancy Szokan, Washington Post
"[T]houghtful and well-written. . . . Shapiro does an excellent job of showing that the realities of genuine science can be as exciting as the fantasies of science fiction."--Nick Rennison, Daily Mail
"[How to Clone a Mammoth] is at once an account of the state of the technology, a sketch of how to proceed, a barrage of as-yet unanswerable questions and a manifesto. . . . The science is fascinating."--Olivia Judson, Financial Times
"This charming volume is a how-to book with a vengeance."--Brian Bethune, Maclean's
"Shapiro… who actually works on the de-extinction of the passenger pigeon and the mammoth, aims to separate science from science fiction. She succeeds brilliantly. This book is likely to prove the definitive guide for non-specialists to the science of de-extinction for some time to come… Shapiro explores the vital questions surrounding the whole subject of de-extinction with great clarity… Shapiro is an acute, lively, sceptical and nuanced writer"--Caspar Henderson, Spectator
Shapiro's thought-provoking book offers excitement and wonder – but also comes with a warning. We must think carefully, not just about how we can achieve this incredible scientific feat, but also about where it is likely to have the most positive (or least negative) impact, and why it is worth the investment and associated risks. [ . . . ] While Shapiro's message throughout How to Clone a Mammoth is unarguably one of caution, she finishes on a hopeful (and awesome) thought: using cutting-edge technology, we might be able to resurrect life that we once thought lost to us for ever, and soon. She paints a scientifically accurate yet magical world where Pleistocene giants might roam the Arctic tundra once again, and where we have the chance to undo some past mistakes – as long as we remember to keep looking towards the future."--Tiffany Taylor, Times Higher Education
"[C]lear and fascinating . . . Shapiro explains complex molecular biology clearly. It really comes alive . . . When she describes her own expeditions."--Shaoni Bhattacharya, New Scientist
"Shapiro's book is a thoughtful how-to guide for the painstaking process of reviving not just mammoths but passenger pigeons and other lost species. Her aim is to separate science from science fiction by taking a critical look at proposals for bringing these animals back."--Allison, Bohac, Science News
"From her front-row seat as one of the pioneers of ancient-DNA research, Shapiro explains the fieldwork, lab science, and prospective ecology involved with the so-far hypothetical endeavor."--Bob Grant, The Scientist
"How To Clone A Mammoth is about as close as you get to sitting down with a nice cup of tea to have a decent chinwag with a mate about resurrecting the woolly mammoth. . . . Refreshingly, she replaces hyperbole with humour to guide the reader through the basics of de-extinction science… that personal touch brings warmth." --Dr Tori Herridge, BBC Focus Magazine
"Skilfully combining accounts of the scientific problems with ethical and practical considerations, the book is an informative and at times highly entertaining account of the life of a modern mammoth hunter. . . . Shapiro lucidly explains all the scientific problems that Jurassic Park conveniently glossed over . . . her real-life tales of mammoth hunting in the Siberian tundra . . . these sections are not so much Jurassic Park as a female geneticist version of Indiana Jones."--William Hartston, Daily Express
"In her new book, Shapiro offers an accessible, rigorous, I-can't-believe-it's-not-sci-fi guide to the world of de-extinction research. You can read the book as a pop primer on genetics, a field guide to future fauna, or as a roadmap to the next generation of conservation science. But reading about these mammoths and Tasmanian tigers, you start to feel that Shapiro is getting at bigger questions. . . . [She] is a lucid, relaxed, and often hilarious guide to the strange world of people who try to resurrect dead species."--Michael Schulson, Religion Dispatches
"[Beth Shapiro's] book exposes the fallacies in our thinking about such activities, as well as the real possibilities and even potential values of restoring some extinct species. This is not a silly book; rather, it is a serious story well told and a fun read."--Buffalo News
"[Shapiro] has skillfully blended cutting edge science with an overview of the ramifications that resurrecting lost fauna might have for the restoration of declining ecosystems."--Everything Dinosaur Blog
"[W]arm and accessible . . . Shapiro's informal approach, peppered with deadpan asides, is a welcome change from the hyperbole and grandstanding that have come to characterise popular debates on rewilding and de-extinction. . . . The open-hearted simplicity of How to Clone a Mammoth provides a great entry point for people who want to join in [the conversation]."--Tori Herridge, Literary Review
"I found this book to be an entertaining and deeply informative read that captures the complexity of both the science and the broader issues raised very well. The next time a film about rampaging Jurassic reptiles is on offer, you could instead settle in with this book and the beverage of your choice and learn about the true potential for species resurrection. Popcorn optional."--A. Rus Hoelzel, Science
"Shapiro's book is fascinating."--The Irish Examiner
"This book is an excellent introduction to the emergent science of de-extinction. Shapiro is a gifted writer who makes a complex subject accessible to readers with little science acumen. . . . The beauty of this work is in its honesty: Shapiro, who is invested in this science as a practitioner, does not attempt to woo the masses. She takes the ethical concerns head on, not as an advocate but as an honest broker."--Choice
"Beth Shapiro is an evolutionary biologist who specialises in ancient DNA. . . . Who better to take us through the technological developments and evidentiary likelihood of recreating extinct species? [A] well-written factual summary . . . playfully set out."--David Callahan, Birdwatch
"Shapiro has done an excellent job."--Ian Simmons, Fortean Times
"Beth Shapiro's 'how-to' manual couldn't be more timely."--New Scientist, a New Scientist best reads from 2015 selection
"This book is careful, accessible, and thoughtful. The author is cautiously enthusiastic about de-extinction research, but she is also very realistic about the challenges and gives serious attention to some of the objections. The volume conveys a sense of excitement about the science, but without the uncritical techno-optimism that one sees in many popular articles."--Derek D. Turner, Quarterly Review of Biology
From the Back Cover
"Bringing a lost species back to life is an exciting prospect and also a scary one. No one is better able to explain the challenges and the potential of the enterprise than Beth Shapiro. How to Clone a Mammoth is an engaging, rigorous, and deeply thoughtful book."--Elizabeth Kolbert, author of The Sixth Extinction: An Unnatural History
"How to Clone a Mammoth is essential reading. Describing the cutting-edge science, and tackling the misleading ideas, surrounding de-extinction, this book immerses us in current discussions as well as the debates that are sure to come."--Joel L. Cracraft, American Museum of Natural History
"How to Clone a Mammoth takes a careful and entertaining look at the possibilities and consequences of bringing such animals as the mammoth and passenger pigeon back from extinction. Well-written and informative, the book explores the science and people involved in these investigations and the difficulties and false leads that have been encountered."--Peter H. Raven, president emeritus, Missouri Botanical Garden
"From basic science to ethics, How to Clone a Mammoth is a thorough and captivating exploration of an area at the leading edge of conservation biology. This book educates readers and entices all of us to delve more deeply into the issues discussed."--Simon Levin, author of Fragile Dominion
Most helpful customer reviews
1 of 1 people found the following review helpful.
How to write a book on cutting-edge science
By Stewart Brand
It is rare that so good a scientist is so good a writer. Shapiro uses her stance of having strong opinions as a gentle form of pedagogy for the lay reader, so that quite arcane details of genomic technology come across clearly and nuances of conservation ethics are laid out in a readable map of forking paths. Best of all for enhancing direct understanding of de-extinction, she writes not as an outsider or journalist but as one of the scientists in the thick of the new field inventing itself.
(Bear in mind I’m also in the thick of this effort, not as a scientist but as the co-founder of Revive & Restore with my wife Ryan Phelan. We both appear in the book because our organization is helping coordinate and fund the various scientists working on de-extinction.)
1 of 1 people found the following review helpful.
Very pragmatic and infectious. Not just how, but ...
By Kurt W. Swenson
Very pragmatic and infectious. Not just how, but why would we, should we and a sense of possibilities to come. A cautious look at what we can do that does not skirt around the risks. This is scientific exploration at a stage where the excitement is palpable. The glimpses into how biology works offers much more than mammoths and passenger pigeons, but these are the trails we find, and if we want to see what is on the other side, we need to forge on. Beth gives you a sense that you are on the journey with her. She doesn't promise that we will see where it all leads in our lifetimes, but she does help you appreciate how fascinating the investigation can be.
0 of 0 people found the following review helpful.
Good Book
By MDW
Well written and very interesting. Genetics is a particular area of interest of mine, and the aspects related to de-extinction, and the tools currently available for DNA manipulation, are well presented. This is the most comprehensive description of de-extinction that I have encountered. Also, the author thankfully found no need to express any personal sexual preferences (unlike Paabo in "Neanderthal Man"). Unfortunately, about half dozen errors remain in the final text that should have been caught in the proofreading phase. Hence, the one-star deduction.
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